Natural Iminosugar (+)-Lentiginosine Inhibits ATPase and Chaperone Activity of Hsp90
Figure 5
Schematic representation of the results obtained from limited proteolysis experiments.
The preferential cleavage sites detected on recombinant Hsp90, and on the Hsp90/1 complex are in black. The Hsp90 N-terminal domain is highlighted in light grey, the middle domain is boxed and the C-terminal domain is highlighted in grey.