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Identification and Characterization of ZEL-H16 as a Novel Agonist of the Histamine H3 Receptor

Figure 4

Competition binding experiments with [3H]-N-α-methylhistamine.

A. H3R/HEK-293 cell membranes with 10 nM [3H]-N-α-methylhistamine; B. Rat cerebral cortex membranes with 2 nM [3H]-N-α-methylhistamine. The presented data are the means ±SE of values from a single experiment performed in duplicate and are representative of three to six separate experiments.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0042185.g004