Structure-Function Relationships of the Mycobacterium tuberculosis Transcription Factor WhiB1
Figure 4
Locations of amino acids required for iron-sulfur cluster acquisition and DNA-binding by WhiB1.
The locations of: the four conserved Cys residues that are required for iron-sulfur cluster acquisition (white text on black background); the predicted β-turn and helix in the C-terminal region; the WhiB1 conserved motifs downstream of the predicted β-turn (boxed); and amino acids that impair DNA-binding in WhiB1 (bold) or WhiBTM4 (underlined) are shown.