Dicer1 Ablation in the Mouse Epididymis Causes Dedifferentiation of the Epithelium and Imbalance in Sex Steroid Signaling
Figure 2
Morphology of 2 month-old mice proximal epididymides.
(A) X-gal staining detecting endogenous β-galactosidase activity in a control mouse initial segment (IS) and proximal corpus (COR). Dicer1fl/fl; Defb41iCre/wt mice display no staining of initial segment and have enlarged efferent ducts (ED). (B) HE staining of the efferent ducts and the proximal epididymis of control and Dicer1fl/fl; Defb41iCre/wt mice. Scale bars 1.5 mm.