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Growth Inhibition and Apoptosis Induced by Osthole, A Natural Coumarin, in Hepatocellular Carcinoma

Figure 1

Osthole Inhibited Cell Proliferation of HCC Cell Lines.

(A) Chemical Structure of osthole (B) Viability of SK-HP-1, SMMC-7721, HepG-2 and Hepa1-6 cells treated with osthole. MTT assay was performed to measure cell growth inhibition rate at 48 h after osthole treatment. (C)(D) Viability of SMMC-7721 and Hepa1-6 cells treated with osthole. MTT assay was performed to measure cell growth inhibition rate at 24 h, 48 h and 72 h after osthole treatment. Data shown were representatives of three experiments.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0037865.g001