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Poly(β-Amino Ester)-Nanoparticle Mediated Transfection of Retinal Pigment Epithelial Cells In Vitro and In Vivo

Figure 9

Biophysical characterization of nanoparticles before and after lyophilization.

(A) Hydrodynamic diameter of freshly prepared DNA/B5-S5-E7 particles versus lyophilized particles (n = 3; bars are standard error). (B) Zeta potential of freshly prepared DNA/B5-S5-E7 particles versus lyophilized particles (n = 3; bars are standard error). Differences in particle size (p = 1) and zeta potential (p = 0.05) are not significant.

Figure 9

doi: https://doi.org/10.1371/journal.pone.0037543.g009