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Tetrahydrouridine Inhibits Cell Proliferation through Cell Cycle Regulation Regardless of Cytidine Deaminase Expression Levels

Figure 2

Tetrahydrouridine (THU) inhibits cell growth in MIAPaCa-2, H1299, and H441.

Tetrahydrouridine (THU) significantly reduced cell growth by colorimetric assay in MIAPaCa-2, H441, and H1229 cell lines as compared with the respective control. Values are means of three independent experiments performed in triplicate. An error bar is presented as S.D. Day4 data were used for the statistical analysis.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0037424.g002