Secretogranin II; a Protein Increased in the Myocardium and Circulation in Heart Failure with Cardioprotective Properties
Figure 1
Left ventricular SgII gene expression in heart failure.
A, SgII mRNA levels in non-infarcted left ventricular tissue during HF development. SgII mRNA levels were 10.5 fold increased (p<0.001) in non-infarcted LV tissue in HF animals (n = 9) compared to sham-operated animals (n = 8). Gene expression was measured by RT-qPCR and is presented as fold change ± SEM. B, LV SgII mRNA levels were closely correlated with CgA mRNA levels in both HF (r = 0.68, p = 0.04) and sham animals (r = 0.81, p = 0.02). **p<0.001.