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Anti-Inflammatory Activities of Inotilone from Phellinus linteus through the Inhibition of MMP-9, NF-κB, and MAPK Activation In Vitro and In Vivo

Figure 3

Effects of inotilone and Indo on hind paw edema induced by Carr in mice (A), the tissue MDA concentration of foot in mice (B), Carr-induced NO (C), and TNF-α (D) concentrations of serum at the 5th

h in mice. Each value represents as mean ± S.E.M. ###p<0.001 as compared with the control group. *p<0.05, **p<0.01, and ***p<0.001 as compared with the Carr group (one-way ANOVA followed by Scheffe’s multiple range test).

Figure 3

doi: https://doi.org/10.1371/journal.pone.0035922.g003