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Mixed Adjuvant Formulations Reveal a New Combination That Elicit Antibody Response Comparable to Freund's Adjuvants

Figure 5

Epitope specificity across all antisera by mAb competition.

Across all samples, the polyclonal antibody responses appeared be mostly CD4bs and CD4i driven, as the antisera could efficiently out-competed mAbs against these two regions (b12 and VRC01 for CD4bs and 17b and E51 for CD4i). Modest to little activities against the V3 loop or the MPER were detected.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0035083.g005