Apilimod Inhibits the Production of IL-12 and IL-23 and Reduces Dendritic Cell Infiltration in Psoriasis
Figure 1
In vitro effect of apilimod on IL-12p70, IL-10, GM-CSF, and IL-6 in human whole blood cells.
Human whole blood from a normal volunteer was stimulated with 0.1% SAC in the presence of different concentrations of apilimod. Supernatants were tested for IL-12p70 (circles), IL-10 (triangles), GM-CSF (diamonds) and IL-6 (squares). Results are representative of one of three individual experiments with whole blood from different volunteers each time.