Salvianolic Acid B Prevents Bone Loss in Prednisone-Treated Rats through Stimulation of Osteogenesis and Bone Marrow Angiogenesis
Figure 5
Effects of different groups on Bone Mineral Density (BMD, mg/cm).
BMD measurements of proximal femur (PF) and whole femur (WF) from vehicle (aging) control (CON), Sal B40 mg/kg/d alone (B40), prednisone alone (GC), GC plus 40 mg Sal B/kg/d (GC+B40) and GC plus 80 mg Sal B/kg/d (GC+B80) treated rats. GC treatment significantly reduced BMD at both sites, while Sal B prevented this reduction in GC treated rats. Value are mean ± SD, *P<0.05, ** P<0.01 vs CON; #P<0.05, # #P<0.01 vs GC.