Salvianolic Acid B Prevents Bone Loss in Prednisone-Treated Rats through Stimulation of Osteogenesis and Bone Marrow Angiogenesis
Figure 4
Biomarker changes in the blood.
Serum calcium (Ca, µg/ml), alkaline phosphatase (ALP, KU/100 ml) and tartrate-resistant acid phosphatase-5b (TRACP-5b, U/L) from vehicle (aging) control (CON), Sal B40 mg/kg/d alone (B40), prednisone alone (GC), GC plus 40 mg Sal B/kg/d (GC+B40) and GC plus 80 mg Sal B/kg/d (GC+B80) treated rats. The GC treatment significantly increased serum calcium and TRACP-5b and reduced ALP, while the Sal B significantly inhibited these GC induced changes. Value are mean ± SD, *P<0.05, ** P<0.01 vs CON; #P<0.05, # #P<0.01 vs GC.