In Vitro Studies on Erythrosine-Based Photodynamic Therapy of Malignant and Pre-Malignant Oral Epithelial Cells
Figure 8
Caspase 3/7 activation in response to PDT was estimated at four different recovery time points post-PDT (0, 2, 4 and 24 hr) in DOK (A) and H357 cells (B) at both low (71.03 µM) and high (1136.50 µM) doses of erythrosine. For both doses, PDT irradiation was done with a fluence of 122.58 J/cm2. In order to bring the data sets of both DOK and H357 cells to the same scale, the luminometer arbitrary values for DOK cells were divided by 10. The values are means of three replicate determinations ± S.D. Statistical analysis was done via student's t-test with significance set at P<0.05 (* indicates statistical comparison as indicated by the lines).