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In Vitro Studies on Erythrosine-Based Photodynamic Therapy of Malignant and Pre-Malignant Oral Epithelial Cells

Figure 6

Scanning Electron Microscopy (SEM) Analysis on H357 cells.

SEM images showing H357 cell morphologies at different recovery time points post-PDT (0, 2 and 24 h) were taken for both low (71.03 µM) and high (1136.50 µM) doses of erythrosine. For both doses, PDT irradiation was done with a fluence of 122.58 J/cm2. These images demonstrate the occurrence of apoptosis (and secondary necrosis) following PDT with low dose erythrosine and necrosis in the high dose condition.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0034475.g006