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In Vitro Studies on Erythrosine-Based Photodynamic Therapy of Malignant and Pre-Malignant Oral Epithelial Cells

Figure 1

Erythrosine Uptake Analysis.

Uptake of erythrosine by pre-malignant (DOK) and malignant (H357) oral epithelial cells was analyzed at 37°C and 4°C. (A) Drug uptake kinetics of erythrosine in DOK cells at 37°C and 4°C. (B) Drug uptake kinetics of erythrosine in H357 cells at 37°C and 4°C. The values are means of four replicate determinations ± S.E.M. Statistical analysis was done via student's t-test with significance set at P<0.05 (* indicates statistical comparison of 37°C data-points vs. the respective data values of 0 µM erythrosine; # indicates comparison of 4°C data-points vs. the respective data values of 0 µM erythrosine and ** indicates comparison between 37°C data-points and the corresponding 4°C data-points).

Figure 1

doi: https://doi.org/10.1371/journal.pone.0034475.g001