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Functional Annotation of Hierarchical Modularity

Figure 2

Functional coherence analysis of protein complexes and pathways.

Functional coherence analysis of protein complexes from MIPS-curated [15], Ho [17], Gavin [18], and Krogan [16] as well as metabolic pathways from KEGG. Comparison between our HMS scoring, cosine similarity with different -value methods from [22], Jaccard similarity with different value methods from [22] and GS [23] methods. (A) Significant Modules (value0.05 and (B) Highly Significant Modules (value).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0033744.g002