A Novel Intravital Method to Evaluate Cerebral Vasospasm in Rat Models of Subarachnoid Hemorrhage: A Study with Synchrotron Radiation Angiography
Figure 2
Line graphs (A and B) show the changes of ICP within 60 minutes following operation in G1, G2, G3 and G4 groups.
Data are means±SD, n = 5 in each group. G1 group: cisterna magna saline injection. G2 group: prechiasmatic cistern saline injection. G3 group: cisterna magna blood injection. G4 group: prechiasmatic cistern blood injection. ICP: intracranial pressure, SAH: subarachnoid hemorrhage. Line graphs (C and D) show the surface CBF changes following 7 days after operation. Data are means±SD, n = 8 in each group. *, p<0.05, G1 vs. G3, G2 vs. G4. CBF: cerebral blood flow. Line graphs (E and F) show the regional CBF (DUR) changes using isotope [125I]-IMP following 1, 3, 5, and 7 days after operation. Data are means±SD, n = 5 in each group. *, p<0.05, G1 vs G3, G2 vs G4. DUR: differential uptake ratio, [125I]-IMP: [125I]N-isopropyl-p-iodoamphetamine.