Adaptation of Mouse Skeletal Muscle to Long-Term Microgravity in the MDS Mission
Figure 5
CSA of different fiber types in muscles from mice flown on board ISS and ground-based controls.
The CSA was measured in individual fiber types in normal laboratory cage controls (open bars, n = 3, data are expressed as means ± SEM), ground control in MDS payload (light blue bars, n = 1), and spaceflight mouse housed in MDS payload for 91 days on board ISS (blue bars, n = 1). A similar CSA reduction of about 35% was observed in all soleus fibers independently of the fiber type, whereas no changes were evident in EDL fibers.