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Adaptation of Mouse Skeletal Muscle to Long-Term Microgravity in the MDS Mission

Figure 3

Fiber typing of muscles flown on board ISS for 91 days and ground-based controls.

Immunofluorescence fiber type identification by means of monoclonal antibodies specific for the different myosin heavy chain isoforms. The different fiber types were identified as described in Materials and Methods. Note the de novo appearance of type 2B fibers. The figure also illustrates the general atrophy of spaceflown soleus muscle fibers, compared to laboratory and ground controls.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0033232.g003