Adaptation of Mouse Skeletal Muscle to Long-Term Microgravity in the MDS Mission
Figure 2
MyHC isoform composition of muscles from mice flown on board ISS and ground-based controls.
A. Representative SDS-PAGE of myosin heavy chain (MyHC) isoform protein bands from EDL and soleus muscle lysates from ground control mice housed for 91 days in a normal laboratory cage (L) or in the MDS payload (G) and from the spaceflight mouse housed in the MDS payload on board ISS for 91 days (F). B. Mean content of MyHC isoform protein bands of laboratory controls housed in laboratory cages (open bars, n = 3, data expressed as means ± SEM), ground control, housed in MDS payload (light blue bars; n = 1), and spaceflight mouse in MDS payload on board ISS for 91 days (blue bars; n = 1).