Genetic Complexity of Fusidic Acid-Resistant Small Colony Variants (SCV) in Staphylococcus aureus
Figure 2
Illustration of a FusE L6-Men SCV derived from S. aureus 8325-4, and how it was evolved back to normal growth by selecting for faster-growing mutants in two steps (clockwise).
A. S. aureus AH001 (WT), normal growth; B. AH386, FusE L6-Men SCV (rplF, menB); C. AH483 (rplF, menB WT); D. AH562 normal growth (rplF WT, menB WT).