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Positron Emission Tomography Imaging of CD105 Expression with a ⁶⁴Cu-Labeled Monoclonal Antibody: NOTA Is Superior to DOTA

Figure 4

Biodistribution studies in 4T1 tumor-bearing mice.

A. Biodistribution of ⁶⁴Cu-NOTA-TRC105 and ⁶⁴Cu-DOTA-TRC105 at 24 h post-injection (n = 3). B. Biodistribution of ⁶⁴Cu-NOTA-TRC105 and ⁶⁴Cu-DOTA-TRC105 at 48 h post-injection (n = 3). *: P<0.05.

doi: https://doi.org/10.1371/journal.pone.0028005.g004