Global Mapping of H3K4me1 and H3K4me3 Reveals the Chromatin State-Based Cell Type-Specific Gene Regulation in Human Treg Cells
Figure 5
Genome-wide distribution and comparison of H3K4me1 modifications between Treg and aTconv cells. Panels A and B
, Distribution and tag density of H3K4me1 enriched peaks. (A) Distribution of H3K4me1 enriched peaks. The number of islands for each sample is listed as the total identified islands (Total), followed by the islands among genomic regions with the corresponding percentage listed in the parenthesis. (B) For each gene, uniquely mapped tags were summed in 125 bp windows from 5 kb upstream of the txStart to the txStart, and from the txEnd to 5 kb downstream. Panels C and D, Comparison of H3K4me1 enriched regions between Treg and aTconv cells. (C) Correlation of H3K4me1 enriched regions between Treg and aTconv cells. Each spot represents a single peak. The X- and Y-axis represent the ratio of the total reads of H3K4me1 enriched peak to the length of this gene in Treg or aTconv cells, respectively. (D) Overlapping H3K4me1 enriched regions between Treg and aTconv cells.