Global Mapping of H3K4me1 and H3K4me3 Reveals the Chromatin State-Based Cell Type-Specific Gene Regulation in Human Treg Cells
Figure 3
Comparison of H3K4me3 enriched regions, proximal promoters or related genes between Treg and aTconv cells. Panel A
, Correlation of H3K4me3 enriched regions between Treg and aTconv cells. Each spot represents a peak. The X- and Y-axis represent the ratio of the total reads of the H3K4me3 enriched peak to the length of the proximal promoter of this gene in Treg or aTconv cells, respectively. Panel B, Overlapping H3K4me3 enriched regions between Treg and aTconv cells. Panel C, Correlation of proximal promoters marked by H3K4me3 between Treg and aTconv cells. Each spot represents an individual peak. The X- and Y-axes are the same as for Panel A. Panel D, The high degree of overlapping proximal promoters marked by H3K4me3 between Treg and aTconv cells. Panel E, Summary of the distribution of overlapping regions enriched by H3K4me3 in Treg and aTconv cells. Panel F, Venn diagram showing the difference of genes associated with H3K4me3 enriched proximal promoters between Treg and aTconv cells.