Structural Basis of Cooperativity in Human UDP-Glucose Dehydrogenase
Figure 6
(A, B) The active site conformations of the open and closed hexamers, respectively. (C, D) The position and hydrogen-bonding pattern of Asp280 in the open and closed hexamers, respectively. The active water molecule is shown as a black sphere. Movie S4 shows a morph between these two structures.