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Lucanthone and Its Derivative Hycanthone Inhibit Apurinic Endonuclease-1 (APE1) by Direct Protein Binding

Figure 7

Lucanthone and hycanthone directly alter APE1 conformation.

CD spectra of APE1 in presence of lucanthone and hycanthone as described in materials and methods, which was analyzed by Dichroweb program CDSSTR.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0023679.g007