Inhibition of Lipoprotein-Associated Phospholipase A2 Ameliorates Inflammation and Decreases Atherosclerotic Plaque Formation in ApoE-Deficient Mice
Figure 4
Composition of atherosclerotic plaques in the aortic sinus.
(A) and (B). Representative examples are provided for VSMC-Actin, macrophage antibody (Mac-2) and trichrome-stained aortic sinus sections. Arrows are indicative of representative regions staining positively for VSMCs and macrophages. The collagen regions are indicated in blue. The bar indicates 400 µm (A) and 200 µm (B), respectively. (C). Comparison of VSMC, macrophage and collagen content between the two groups (N = 7 per group), *p<0.05 and **p<0.01 vs. vehicle.