Inhibition of Lipoprotein-Associated Phospholipase A2 Ameliorates Inflammation and Decreases Atherosclerotic Plaque Formation in ApoE-Deficient Mice
Figure 3
Inhibition of lp-PLA2 decreases the atherosclerotic area.
(A). Representative en face atherosclerotic aorta preparations stained with Sudan IV. (B). Comparison of plaque sizes between the vehicle and darapladib groups (N = 13 per group). The area stained with dye is expressed as a percentage of the total surface area. The mean is depicted as a single horizontal line.