Diversification and Molecular Evolution of ATOH8, a Gene Encoding a bHLH Transcription Factor
Figure 5
CpG islands and TATA elements in the upstream region of ATOH8 start codon.
In mammals, the upstream region of ATOH8 coding region is characteristic of CpG islands, of which the human ATOH8 has the longest CpG islands. No TATA elements (green diamonds) are found. In chicken, both CpG islands and TATA elements are found in ATOH8 upstream region. In frog and zebrafish, there are no CpG islands but TATA elements present in the upstream region. From chicken, frog to zebrafish, the number of TATA elements increases.