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Prolonged Depression-Like Behavior Caused by Immune Challenge: Influence of Mouse Strain and Social Environment

Figure 7

Effect of LPS (0.83 mg/kg injected IP), relative to vehicle (VEH), on plasma concentrations of interleukin-6 as recorded 1 and 28 days after treatment under single and group housing conditions.

Trunk blood of CD1 (A) and C57BL/6 (B) mice for the interleukin-6 assay was taken 30 min after the FST had been started. The values are means+SEM, n = 7–8. ** P<0.05, *** P<0.01 versus vehicle-treated mice at the same time point post-treatment.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0020719.g007