Anti-Influenza Activity of Marchantins, Macrocyclic Bisbibenzyls Contained in Liverworts
Figure 5
Decrease of the viral infectivity titer by marchantins.
Decrease of viral infectivity titer of influenza B viral by phytochemicals. MDCK cells were treated with influenza B/Malashia/2506/2004 virus. The cells were then treated with various concentrations of phytochemicals (3.1–50 µM), some of which decreased viral infectivity titer. DMSO was used as the phytochemicals solvent. (A) Viral growth curve under exposure to various concentrations of marchantins. The horizontal axis is the culture time and the vertical axis is the logarithm of virus infectivity titer (focus formation unit (FFU)). (B) Viral growth curve in the presence of marchantins and comparisons of the same concentration. The horizontal axis is the culture time and the vertical axis is the logarithm of virus infectivity titer (focus formation unit (FFU)).