Phosphorylation-Dependent 14-3-3 Binding to LRRK2 Is Impaired by Common Mutations of Familial Parkinson's Disease
Figure 4
S935A mutation does not affect LRRK2 dimerization.
(A, B) FLAG-LRRK2 WT or S935A mutant construct was co-transfected with HA-LRRK2 constructs. The Co-IP assay was performed using either anti-HA (A) or anti-FLAG (B) antibody, followed by Western blot analysis using the indicated antibodies.