Mycoplasma Contamination Revisited: Mesenchymal Stromal Cells Harboring Mycoplasma hyorhinis Potently Inhibit Lymphocyte Proliferation In Vitro
Figure 6
Mycoplasma infection spreads rapidly in MLR cultures.
Mycoplasma-positive MSC were cultured either alone (right panel) or together with PVG responder cells and irradiated BN cells (left panel) for 3 d. Supernatants were collected at the indicated time points and tested by PCR. The log dilutions of MSC are denoted; ctrl, no MSC added. Mycoplasma was detectable at considerably lower MSC concentrations when co-cultured with lymphocytes.