In Vitro and In Vivo Anti-Inflammatory Activity of 17-O-Acetylacuminolide through the Inhibition of Cytokines, NF-κB Translocation and IKKβ Activity
Figure 5
The inhibitory effect of 17-O-acetylacuminolide (AA) on cytokine mRNA.
Cells were treated and mRNA was quantified as described in materials and methods. Data presented is of AA inhibition of TNF and IL-1β mRNA induction and is representative of three independent experiments. Data was analyzed using one-way ANOVA with Tukey's post hoc test (*** p<0.001).