Ultraviolet Irradiation Induces the Accumulation of Chondroitin Sulfate, but Not Other Glycosaminoglycans, in Human Skin
Figure 5
Time course for changes in HA content of UVB-irradiated skin.
Normal human volunteers were exposed to 2X MED of UVB. Biopsies were taken 1, 2, and 3 days after irradiation. HA was labeled with biotinylated HABP and visualized using a peroxidase system. Shown are stains of (a) control tissue and tissue taken (b) 24, (c) 48, and (d) 72 hours post-irradiation. The images in this figure are of tissue from the same patient. (size bars = 62.5 µm).