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ATM Modulates the Loading of Recombination Proteins onto a Chromosomal Translocation Breakpoint Hotspot

Figure 5

INO80 loading on the BCR after etoposide treatment.

(A-C) ChIP analysis of BV173 (A), 11-4 (B) and AT5BIVA (C) cells after etoposide exposure was performed with antibodies against INO80 as described in Figure 3. Values are the means ± SE from three independent experiments. (D) Immunoblotting analysis of BV173, AT5BIVA and 11-4 cells was performed using anti-INO80 antibodies. RAD21 was used as a loading control. * P<0.05 (compared to βG by Student's t test).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0013554.g005