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A Distinct Expression Pattern in Mammalian Testes Indicates a Conserved Role for NANOG in Spermatogenesis

Figure 3

Models for the dynamic expression of NANOG in the epithelial cycle of murine (top) and canine (bottom) spermatogenesis.

Each column represents the combination of different cell types that are present in seminiferous tubules at that specific stage. Roman figures = stage of the epithelial cycle, In = intermediate spermatogonia, B = type B spermatogonia, Pl = pre-leptotene stage, L = leptotene stage, Z = zygotene stage, P = pachytene stage, D = diplotene stage, 2nd = generation of secondary spermatocytes, 1–16 = steps in spermiogenesis. Cell types that express NANOG are outlined in red and cell types that do not express NANOG have black and grey symbols.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0010987.g003