The Genome of a Bacillus Isolate Causing Anthrax in Chimpanzees Combines Chromosomal Properties of B. cereus with B. anthracis Virulence Plasmids
Figure 2
Circular maps of “B. cereus var. anthracis” strain CI chromosome and plasmids.
(A) Circular map of Bc var. anth. CI chromosome in comparison with chromosomes of the B. cereus group. The map is oriented with the origin of replication on top, the direction of replication is depicted by arrowheads. The rings display from outside to the center a) ORFs, clockwise transcribed genes in gold, counterclockwise in green, b) GC-skew c) stable RNAs genes in red d) genomic islands in green, the flagella locus in light blue and repetitive elements in blue, e) GC-content, f)–l) BiBlast comparisons of strain CI with f) B. anthracis Ames Ancestor, g) B. anthracis Ames, h) B. anthracis Sterne, i) B. cereus ATCC 10987, j) B. cereus E33L, k) B. thuringiensis serovar konkukian strain 97-27, and l) B. weihenstephanensis strain KBA4. Shared genes are displayed in grey, missing genes in red, white regions refer to regions of Bc var. anth. strain CI that do not code for proteins. Known genomic islands are indicated by roman numbers. (B) Circular maps of the Bc var. anth. CI plasmids pCI-XO1, pCI-XO2 and pCI-14, the sizes of the circles are correlated to relative size of the plasmids. Clockwise transcribed genes are depicted in gold, counter clockwise transcribed genes in green. The inner ring displays the GC-content. Invertible elements A and B in pCI-XO1 are marked in light blue, virulence correlated genes in element B are marked red. Genes for capsule synthesis in pCI-XO2 are depicted in red.