Bare Bones Pattern Formation: A Core Regulatory Network in Varying Geometries Reproduces Major Features of Vertebrate Limb Development and Evolution
Figure 2
Simulation of chicken wing development.
(Left) Developmental progression of chicken forelimb between days 3 and 7 of development (indicated by the corresponding Hamburger-Hamilton stages). Early cartilage, including precartilage condensations, shown in light blue; definitive cartilage shown in darker blue. Based on ref. [23]. (Right) A sequence of snapshots from the simulation of normal limb development. See File S1 for the “standard” set of parameters used. Time is in arbitrary units, but can be used for comparison between different simulations.