A Locked Nucleic Acid Antisense Oligonucleotide (LNA) Silences PCSK9 and Enhances LDLR Expression In Vitro and In Vivo
Figure 6
HepG2 cells were transfected for 4h with water for mock or 10 and 25 nM LNA ASO using Lipofectamine 2000 and incubated for 48h. The cells were then treated with Alamar blue reagent and analyzed on an Elisa plate reader for cell viability.