A Locked Nucleic Acid Antisense Oligonucleotide (LNA) Silences PCSK9 and Enhances LDLR Expression In Vitro and In Vivo
Figure 5
Cell surface expression of LDLR in LNA ASO treated HepG2 cells.
Cells were transfected with 10 and 25 nM LNA ASO, and after 72 h FACS analysis was done to evaluate surface expression of LDLR using anti human LDLR as primary antibody and a suitable secondary antibody labeled with alexa 647.