A Locked Nucleic Acid Antisense Oligonucleotide (LNA) Silences PCSK9 and Enhances LDLR Expression In Vitro and In Vivo
Figure 3
QPCR analysis of HMGCoAR mRNA.
(A) HepG2 cells and (B) β-TC3 cells transfected with 10 and 25 nM LNA ASO and analyzed at 24 h and 48 h post-transfection. Human S14 and mouse S16 mRNAs were used for normalization.