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Accelerated Wound Healing by mTOR Activation in Genetically Defined Mouse Models

Figure 5

Accelerated wound closure in upon epithelial Tsc1 excision.

Representative photographs of control and K14Cre Tsc1F/F mice at the indicated days after wounding. (B) Quantification of the wound area. Results represent the mean ± s.e.m; n = 8 for each time point and genotype. (***p<0.0001) (C) Graphic representation of the percentage of animals displaying open wounds in control mice (A) and K14Cre Tsc1F/F mice (B) at each depicted time (days) (*p = 0.0150).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0010643.g005