Cancer Testis Antigen Vaccination Affords Long-Term Protection in a Murine Model of Ovarian Cancer
Figure 2
(a, b, c, d) Tumor growth in ID8-injected mice.
Shows the progressive formation of ascites/tumors when i.p. injected with ID8 cells. ID8 injected mice are shown as m1-m5. Control mice were injected with PBS alone. 1a shows mice injected with 105 ID8 cells. The tumors did not reach a significant size until after 150 days. 2b shows the progressive formation of ascites/tumors when i.p. injected with 5×105 ID8 cells. The tumors did not reach a significant size until after 120 days. 2c shows the progressive formation of ascites/tumors when i.p. injected with 106 ID8 cells. The tumors reached a significant size in 90–120 days. 2d shows the progressive formation of ascites/tumors when i.p. injected with 2×106 ID8 cells. The tumors reached a significant size in 35–60 days (p<0,0001); a visible enlargement of the mice was noticed at 30 days.