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Attenuation of Reactive Gliosis Does Not Affect Infarct Volume in Neonatal Hypoxic-Ischemic Brain Injury in Mice

Figure 2

Hemisphere and infarct volume in GFAP−/−Vim−/− and wild-type mice after hypoxia-ischemia.

Volume measurements in MAP-2 stained sections from GFAP−/−Vim−/− (GV) (n = 23) and wild-type (WT) (n = 19) mice at P12 and P31, i.e. 3 and 22 days after hypoxia-ischemia. (A) Ipsi- and contralateral hemisphere volume in GFAP−/−Vim−/− and wild-type mice. (B) Infarction volume in GFAP−/−Vim−/− and wild-type mice. Data are mean ± SD.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0010397.g002