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Metastasis-Inducing S100A4 and RANTES Cooperate in Promoting Tumor Progression in Mice

Figure 5

S100A4-mediated activation of cytokines in VMR cells.

(A) Cytokine antibody array analysis of CM from VMR cells, unstimulated and stimulated with 0.5 µg/ml recombinant oligomeric S100A4. Upregulated cytokines are marked with white rectangles. (B) Kinetics of RANTES transactivation in response to 0.5 µg/ml recombinant oligomeric S100A4 (qPCR). (C) Western blot analysis of S100A4-mediated upregulation of RANTES in VMR-CM.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0010374.g005