Distinct Expression Levels and Patterns of Stem Cell Marker, Aldehyde Dehydrogenase Isoform 1 (ALDH1), in Human Epithelial Cancers
Figure 2
Expression and distribution of ALDH1 protein in human epithelial tumors.
Tissue microarrays were used to characterize the expression and distribution of ALDH1 in cancers (n = 353). A. Expression of ALDH1 in the corresponding normal tissues. B. ALDH1+ tumor-infiltrating cells were detected in the stroma. C. Expression of ALDH1 in epithelial tumors. Percentage of ALDH1+ tumor cells was summarized. D. High percentage of ALDH1+ cells was associated with poor clinical outcomes in serous ovarian cancer.