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Reconstruction of Gene Regulatory Modules in Cancer Cell Cycle by Multi-Source Data Integration

Figure 5

Binding site enrichment analysis for gene clusters.

Sequence logos represent the motif significantly overrepresented in individual gene cluster associated with their predicted upstream transcription factors, according to the WebMOTIFS discovery algorithm [48]. Individual base letter height indicates level of conservation within each binding site position. Conserved binding motifs are the conserved binding sequences used in the WebMOTIFS discovery algorithm.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0010268.g005