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Optimized Expression of Full-Length IgG1 Antibody in a Common E. coli Strain

Figure 2

Initial bacterial IgG expression and periplasmic extraction.

(A and B) Non-reducing and reducing immunoblot of periplasmic extract from overnight expression of 4G2 in HB2151 (HB) and BL21(DE3) (BL) E. coli strains, respectively. All blots were probed with anti-Human Fc-HRPO.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0010261.g002